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lipB lipB lipA lipA Hhal_1014 Hhal_1014 gcvH gcvH Hhal_1012 Hhal_1012 Hhal_1013 Hhal_1013 Hhal_0003 Hhal_0003 Hhal_0018 Hhal_0018 Hhal_0598 Hhal_0598 mrdA mrdA Hhal_1085 Hhal_1085
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (217 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.998
Hhal_1014
PFAM: protein of unknown function DUF493; KEGG: aeh:Mlg_0178 protein of unknown function DUF493; Belongs to the UPF0250 family.
  
  
 0.889
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.872
Hhal_1012
Penicillin-binding protein 6, Serine peptidase, MEROPS family S11; PFAM: beta-lactamase; peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: aeh:Mlg_0176 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
      0.851
Hhal_1013
Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase; PFAM: aminotransferase, class IV; KEGG: aeh:Mlg_0177 aminotransferase, class IV.
  
    0.819
Hhal_0003
3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: beta-ketoacyl synthase; KEGG: noc:Noc_1663 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
 0.813
Hhal_0018
3-oxoacyl-[acyl-carrier-protein] synthase I; PFAM: beta-ketoacyl synthase; KEGG: aeh:Mlg_1373 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
 0.813
Hhal_0598
Enoyl-[acyl-carrier-protein] reductase (NADH); PFAM: short-chain dehydrogenase/reductase SDR; KEGG: aeh:Mlg_2277 short-chain dehydrogenase/reductase SDR.
     
  0.800
mrdA
Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.670
Hhal_1085
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 
 0.664
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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