node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvan_4116 | atpA | Mvan_4116 | Mvan_4330 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | 0.938 |
Mvan_4116 | atpB | Mvan_4116 | Mvan_4334 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | ATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.556 |
Mvan_4116 | atpC | Mvan_4116 | Mvan_4327 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.942 |
Mvan_4116 | atpD | Mvan_4116 | Mvan_4328 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 0.814 |
Mvan_4116 | atpE | Mvan_4116 | Mvan_4333 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.592 |
Mvan_4116 | atpF | Mvan_4116 | Mvan_4332 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | H+-transporting two-sector ATPase, B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.503 |
Mvan_4116 | atpFH | Mvan_4116 | Mvan_4331 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). | 0.968 |
Mvan_4116 | atpG | Mvan_4116 | Mvan_4329 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | 0.944 |
Mvan_4116 | kgd | Mvan_4116 | Mvan_4477 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | 2-oxoglutarate dehydrogenase E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate ( [...] | 0.972 |
Mvan_4116 | ppa | Mvan_4116 | Mvan_5381 | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.519 |
atpA | Mvan_4116 | Mvan_4330 | Mvan_4116 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit. | 0.938 |
atpA | atpB | Mvan_4330 | Mvan_4334 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.999 |
atpA | atpC | Mvan_4330 | Mvan_4327 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.999 |
atpA | atpD | Mvan_4330 | Mvan_4328 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 0.999 |
atpA | atpE | Mvan_4330 | Mvan_4333 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.999 |
atpA | atpF | Mvan_4330 | Mvan_4332 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | H+-transporting two-sector ATPase, B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.999 |
atpA | atpFH | Mvan_4330 | Mvan_4331 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP synthase F1 subcomplex delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). | 0.999 |
atpA | atpG | Mvan_4330 | Mvan_4329 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | ATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. | 0.999 |
atpA | kgd | Mvan_4330 | Mvan_4477 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | 2-oxoglutarate dehydrogenase E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate ( [...] | 0.955 |
atpA | ppa | Mvan_4330 | Mvan_5381 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. | Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.949 |