STRINGSTRING
argR argR Clos_1604 Clos_1604 Clos_1606 Clos_1606 Clos_2419 Clos_2419 birA birA Clos_1603 Clos_1603 Clos_1602 Clos_1602 dxs dxs pheT pheT nusB nusB Clos_1609 Clos_1609
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
argRArginine repressor, ArgR; Regulates arginine biosynthesis genes. (149 aa)    
Predicted Functional Partners:
Clos_1604
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.907
Clos_1606
TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: cbo:CBO1880 methyltransferase.
  
    0.758
Clos_2419
PFAM: aminotransferase class-III; KEGG: tte:TTE2339 PLP-dependent aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.722
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.706
Clos_1603
KEGG: tte:TTE1303 sporulation protein IVB; TIGRFAM: Peptidase S55 sporulation stage IV protein B; PFAM: peptidase S55 SpoIVB; SMART: PDZ/DHR/GLGF domain protein.
       0.694
Clos_1602
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
    0.682
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
  
    0.672
pheT
KEGG: cdf:CD0700 phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.656
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
 
    0.650
Clos_1609
PFAM: Polyprenyl synthetase; KEGG: cdf:CD1205 geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
     
 0.631
Your Current Organism:
Alkaliphilus oremlandii
NCBI taxonomy Id: 350688
Other names: A. oremlandii OhILAs, Alkaliphilus oremlandii OhILAs, Alkaliphilus oremlandii str. OhILAs, Alkaliphilus oremlandii strain OhILAs, Clostridium oremlandii OhILAs, Clostridium sp. OhILAs
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