node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maqu_0074 | mtnB | Maqu_0074 | Maqu_0907 | PFAM: initiation factor 2B related; KEGG: tko:TK1047 translation initiation factor eIF-2B, delta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.649 |
Maqu_0074 | mtnC | Maqu_0074 | Maqu_0909 | PFAM: initiation factor 2B related; KEGG: tko:TK1047 translation initiation factor eIF-2B, delta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.444 |
Maqu_0074 | mtnD | Maqu_0074 | Maqu_0908 | PFAM: initiation factor 2B related; KEGG: tko:TK1047 translation initiation factor eIF-2B, delta subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. | Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.508 |
Maqu_0905 | Maqu_0906 | Maqu_0905 | Maqu_0906 | PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hch:HCH_05037 aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein. | Isoquinoline 1-oxidoreductase; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: hch:HCH_05036 aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein. | 0.999 |
Maqu_0905 | Maqu_0910 | Maqu_0905 | Maqu_0910 | PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hch:HCH_05037 aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein. | KEGG: hch:HCH_01854 hypothetical protein. | 0.529 |
Maqu_0905 | mtnB | Maqu_0905 | Maqu_0907 | PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hch:HCH_05037 aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.569 |
Maqu_0905 | mtnC | Maqu_0905 | Maqu_0909 | PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hch:HCH_05037 aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.539 |
Maqu_0905 | mtnD | Maqu_0905 | Maqu_0908 | PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hch:HCH_05037 aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein. | Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.539 |
Maqu_0906 | Maqu_0905 | Maqu_0906 | Maqu_0905 | Isoquinoline 1-oxidoreductase; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: hch:HCH_05036 aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein. | PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hch:HCH_05037 aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein. | 0.999 |
Maqu_0906 | Maqu_0910 | Maqu_0906 | Maqu_0910 | Isoquinoline 1-oxidoreductase; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: hch:HCH_05036 aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein. | KEGG: hch:HCH_01854 hypothetical protein. | 0.529 |
Maqu_0906 | mtnB | Maqu_0906 | Maqu_0907 | Isoquinoline 1-oxidoreductase; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: hch:HCH_05036 aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.539 |
Maqu_0906 | mtnC | Maqu_0906 | Maqu_0909 | Isoquinoline 1-oxidoreductase; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: hch:HCH_05036 aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.539 |
Maqu_0906 | mtnD | Maqu_0906 | Maqu_0908 | Isoquinoline 1-oxidoreductase; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: hch:HCH_05036 aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein. | Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.539 |
Maqu_0910 | Maqu_0905 | Maqu_0910 | Maqu_0905 | KEGG: hch:HCH_01854 hypothetical protein. | PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: hch:HCH_05037 aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS-like protein. | 0.529 |
Maqu_0910 | Maqu_0906 | Maqu_0910 | Maqu_0906 | KEGG: hch:HCH_01854 hypothetical protein. | Isoquinoline 1-oxidoreductase; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: hch:HCH_05036 aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL-like protein. | 0.529 |
Maqu_0910 | mtnB | Maqu_0910 | Maqu_0907 | KEGG: hch:HCH_01854 hypothetical protein. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.757 |
Maqu_0910 | mtnC | Maqu_0910 | Maqu_0909 | KEGG: hch:HCH_01854 hypothetical protein. | Acireductone synthase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.757 |
Maqu_0910 | mtnD | Maqu_0910 | Maqu_0908 | KEGG: hch:HCH_01854 hypothetical protein. | Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.757 |
Maqu_1526 | Maqu_3044 | Maqu_1526 | Maqu_3044 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: hch:HCH_01531 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.999 |
Maqu_1526 | mtnA | Maqu_1526 | Maqu_2493 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Translation initiation factor 2B subunit I family (IF-2BI); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.804 |