STRINGSTRING
htpG htpG dnaJ dnaJ Ping_0515 Ping_0515 dnaK dnaK Ping_2692 Ping_2692 Ping_1232 Ping_1232 Ping_1233 Ping_1233 hscA hscA Ping_3561 Ping_3561 Ping_3719 Ping_3719 Ping_2499 Ping_2499
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
htpGHeat shock protein Hsp90; Molecular chaperone. Has ATPase activity. (634 aa)    
Predicted Functional Partners:
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 0.974
Ping_0515
KEGG: pat:Patl_2983 putative heat shock protein 70 family protein.
   
 0.962
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.962
Ping_2692
PFAM: Heat shock protein 70; KEGG: bth:BT4602 chaperone protein DnaK.
   
 0.962
Ping_1232
Chaperone DnaK-related protein; KEGG: hch:HCH_03650 molecular chaperone; Belongs to the heat shock protein 70 family.
   
 0.960
Ping_1233
Chaperone DnaK-related protein; KEGG: hch:HCH_03649 molecular chaperone.
   
 0.960
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
 
 
 0.960
Ping_3561
Plasmid segregation actin-type ATPase ParM; PFAM: StbA family protein; KEGG: ppr:PBPRA0050 hypothetical StbA plasmid stable inheritance protein.
   
 0.960
Ping_3719
Sensor histidine kinase with ATPase domain; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: vvy:VVA0933 signal transduction histidine kinase.
   
 0.924
Ping_2499
PFAM: heat shock protein DnaJ domain protein; KEGG: hch:HCH_06092 DnaJ-class molecular chaperone.
 
 0.916
Your Current Organism:
Psychromonas ingrahamii
NCBI taxonomy Id: 357804
Other names: P. ingrahamii 37, Psychromonas ingrahamii 37, Psychromonas ingrahamii str. 37, Psychromonas ingrahamii strain 37, gas vacuolate str. 37
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