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lig lig ligA ligA leuS leuS Abu_1068 Abu_1068 Abu_1069 Abu_1069 ruvB ruvB polA polA Abu_2085 Abu_2085 rpoC rpoC topA topA ruvA ruvA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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ligDNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (648 aa)    
Predicted Functional Partners:
ligA
Pfam match to PF01068 DNA_ligase_A_M, score 43.2, E-value 7.9E-013.
    
 0.925
leuS
leucyl-tRNA synthetase; Pfam match to PF00133 tRNA-synt_1, score 62.3, E-value 3.5E-017; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 
 0.776
Abu_1068
Glutathionylspermidine synthase family protein; Pfam match to PF03738 GSP_synth, score 594.4, E-value 9.8E-176.
       0.741
Abu_1069
Conserved hypothetical lipoprotein.
       0.741
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
   
 0.738
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.730
Abu_2085
ATP-dependent DNA helicase, UvrD/PcrA family; Pfam match to PF00580 UvrD-helicase, score 578.8, E-value 4.9E-171.
 
  
 0.617
rpoC
DNA-directed RNA polymerase, beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.596
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.590
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
   
 0.586
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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