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mdh mdh fumA fumA fumC fumC gltA gltA icd icd pycB1 pycB1 maeA maeA pckA pckA aspB3 aspB3 mqo mqo accC2 accC2
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (314 aa)    
Predicted Functional Partners:
fumA
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.995
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.986
gltA
Pfam match to PF00285 Citrate_synt, score 541.9, E-value 6.2E-160; Belongs to the citrate synthase family.
  
 0.976
icd
Isocitrate dehydrogenase; Pfam match to PF03971 IDH, score 1106, E-value 0.0; Belongs to the monomeric-type IDH family.
  
  
 0.963
pycB1
Pyruvate/oxaloacetate carboxyltransferase; Pfam matches to PF00364 Biotin_lipoyl, score 83.9, E-value 4.4E-022, and to PF00682 HMGL-like, score -49.1, E-value 6.8E-005.
    
 0.949
maeA
NAD-dependent malic enzyme; Pfam matches to PF03949 Malic_M, score 344.3, E-value 1.8E-100, and to PF00390 malic, score 255.6, E-value 9.5E-074.
  
 0.946
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.926
aspB3
Aspartate aminotransferase, aminotransferase, classes I and II; Pfam match to PF00155 Aminotran_1_2, score 287.2, E-value 2.8E-083.
  
 0.923
mqo
Malate:quinone oxidoreductase; Pfam match to PF01266 DAO, score 44.9, E-value 1.5E-012.
    
 0.919
accC2
Acetyl CoA carboxylase, biotin carboxylase subunit; Pfam matches to PF02786 CPSase_L_D2, score 350.1, E-value 3.4E-102, and to PF02785 Biotin_carb_C, score 211.5, E-value 1.7E-060, and to PF00289 CPSase_L_chain, score 135.4, E-value 1.4E-037.
   
 0.916
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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