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ung ung xth xth dnaN dnaN trpD trpD nth nth nfo nfo Abu_2148 Abu_2148 ilvB ilvB polA polA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (215 aa)    
Predicted Functional Partners:
xth
Exodeoxyribonuclease; Pfam match to PF03372 Exo_endo_phos, score 173.8, E-value 3.9E-049.
   
 0.711
dnaN
DNA polymerase III, beta subunit; Pfam matches to PF00712 DNA_pol3_beta, score 79.7, E-value 8.1E-021, and to PF02767 DNA_pol3_beta_2, score 52.1, E-value 1.9E-015.
   
 
 0.677
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
      0.653
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.644
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
   
 
 0.526
Abu_2148
Aldehyde dehydrogenase family protein; Pfam match to PF00171 Aldedh, score 471.2, E-value 1.2E-138.
     
 0.520
ilvB
Acetolactate synthase; Pfam matches to PF02775 TPP_enzyme_C, score 197.9, E-value 1.4E-061, and to PF02776 TPP_enzyme_N, score 176.6, E-value 1.4E-050, and to PF00205 TPP_enzyme_M, score 73.7, E-value 4.3E-021.
       0.476
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.457
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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