node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tpen_0376 | Tpen_0512 | Tpen_0376 | Tpen_0512 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | 0.984 |
Tpen_0376 | csl4 | Tpen_0376 | Tpen_0521 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.951 |
Tpen_0376 | nep1 | Tpen_0376 | Tpen_0557 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
Tpen_0376 | rps11 | Tpen_0376 | Tpen_0257 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.979 |
Tpen_0376 | rps4 | Tpen_0376 | Tpen_0258 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.980 |
Tpen_0376 | rrp4 | Tpen_0376 | Tpen_0582 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.950 |
Tpen_0376 | rrp41 | Tpen_0376 | Tpen_0581 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | Ribosomal RNA-processing protein RRP41/SKI6; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.931 |
Tpen_0376 | rrp42 | Tpen_0376 | Tpen_0580 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.942 |
Tpen_0376 | rtcA | Tpen_0376 | Tpen_0217 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | RNA-3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.952 |
Tpen_0512 | Tpen_0376 | Tpen_0512 | Tpen_0376 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | 0.984 |
Tpen_0512 | csl4 | Tpen_0512 | Tpen_0521 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.973 |
Tpen_0512 | dnaG | Tpen_0512 | Tpen_0501 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.507 |
Tpen_0512 | nep1 | Tpen_0512 | Tpen_0557 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
Tpen_0512 | rps11 | Tpen_0512 | Tpen_0257 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. | 0.995 |
Tpen_0512 | rps4 | Tpen_0512 | Tpen_0258 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.997 |
Tpen_0512 | rrp4 | Tpen_0512 | Tpen_0582 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | Ribosomal RNA-processing protein RRP4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.952 |
Tpen_0512 | rrp41 | Tpen_0512 | Tpen_0581 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | Ribosomal RNA-processing protein RRP41/SKI6; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.944 |
Tpen_0512 | rrp42 | Tpen_0512 | Tpen_0580 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | Ribosomal RNA-processing protein RRP42; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.944 |
Tpen_0512 | rtcA | Tpen_0512 | Tpen_0217 | PFAM: KH, type 1, domain protein; SMART: KH domain protein; KEGG: mja:MJ0443 hypothetical protein. | RNA-3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.965 |
csl4 | Tpen_0376 | Tpen_0521 | Tpen_0376 | RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. | 0.951 |