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dapE dapE dapF dapF dapA dapA dapD dapD lysA lysA fliG fliG metG metG thrA thrA tktB tktB serC serC rpmF rpmF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (376 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
    
 0.981
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.855
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; COG_category E;COG_number COG2171; DapD.
  
  
 0.819
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.796
fliG
Flagellar motor switch protein; COG_category N;COG_number COG1536; FliG.
   
   0.685
metG
methionyl-tRNA synthetase; COG_category J;COG_number COG0143; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.676
thrA
Aspartokinase I / homoserine dehydrogenase I; COG_category E;COG_number COG0460, COG0527; ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.
     
 0.615
tktB
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
  
 0.578
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.575
rpmF
50S ribosomal protein L32; COG_category J;COG_number COG0333; RpmF; Belongs to the bacterial ribosomal protein bL32 family.
  
    0.574
Your Current Organism:
Buchnera aphidicola BCc
NCBI taxonomy Id: 372461
Other names: B. aphidicola BCc, Buchnera aphidicola str. Cc (Cinara cedri)
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