STRINGSTRING
ung ung dnaN dnaN polA polA dut dut nfo nfo thrA thrA ahpC ahpC pheT pheT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (227 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, b subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
   
   0.798
polA
5'-3' exonuclease domain of DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
  
 0.681
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG_category F;COG_number COG0756; Dut.
  
 
 0.598
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
   
 
 0.588
thrA
Aspartokinase I / homoserine dehydrogenase I; COG_category E;COG_number COG0460, COG0527; ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.
       0.530
ahpC
Alkyl hydroperoxide reductase, C22 subunit, thioredoxin-like; COG_category O;COG_number COG0450; AhpC.
       0.527
pheT
phenylalanyl-tRNA synthetase, b subunit; COG_category J;COG_number COG0072; PheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.511
Your Current Organism:
Buchnera aphidicola BCc
NCBI taxonomy Id: 372461
Other names: B. aphidicola BCc, Buchnera aphidicola str. Cc (Cinara cedri)
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