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hutI hutI hutU hutU hutG hutG hutH hutH AHA_3390 AHA_3390 hutC hutC AHA_1921 AHA_1921 purB purB ilvA ilvA AHA_4006 AHA_4006 AHA_0375 AHA_0375
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hutIImidazolonepropionase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01224; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (434 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 
 0.999
hutG
Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
 
 0.997
hutH
Histidine ammonia-lyase; Identified by match to protein family HMM PF00221; match to protein family HMM TIGR01225.
 
  
 0.989
AHA_3390
Phenylalanine and histidine ammonia-lyase; Identified by match to protein family HMM PF00221.
 
  
 0.941
hutC
Histidine utilization repressor; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02018.
 
  
 0.892
AHA_1921
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
     
 0.535
purB
Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  
 0.532
ilvA
Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
  
 0.532
AHA_4006
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit DhaM; Identified by match to protein family HMM PF00381; match to protein family HMM PF03610; match to protein family HMM TIGR01003; match to protein family HMM TIGR02364.
     
 0.531
AHA_0375
Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
       0.530
Your Current Organism:
Aeromonas hydrophila
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
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