node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fnod_0198 | pyrG | Fnod_0198 | Fnod_0197 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: tma:TM0804 histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.791 |
Fnod_0198 | uvrC | Fnod_0198 | Fnod_0196 | TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: tma:TM0804 histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.600 |
Fnod_0363 | Fnod_0683 | Fnod_0363 | Fnod_0683 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | 0.457 |
Fnod_0363 | Fnod_0721 | Fnod_0363 | Fnod_0721 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase. | 0.714 |
Fnod_0363 | polA | Fnod_0363 | Fnod_0360 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.849 |
Fnod_0363 | uvrA | Fnod_0363 | Fnod_1525 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.449 |
Fnod_0363 | uvrB | Fnod_0363 | Fnod_0489 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.407 |
Fnod_0363 | uvrC | Fnod_0363 | Fnod_0196 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.639 |
Fnod_0683 | Fnod_0363 | Fnod_0683 | Fnod_0363 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.457 |
Fnod_0683 | Fnod_0721 | Fnod_0683 | Fnod_0721 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase. | 0.811 |
Fnod_0683 | mutL | Fnod_0683 | Fnod_1711 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.561 |
Fnod_0683 | polA | Fnod_0683 | Fnod_0360 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.733 |
Fnod_0683 | uvrA | Fnod_0683 | Fnod_1525 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.525 |
Fnod_0683 | uvrB | Fnod_0683 | Fnod_0489 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.619 |
Fnod_0683 | uvrC | Fnod_0683 | Fnod_0196 | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.593 |
Fnod_0721 | Fnod_0363 | Fnod_0721 | Fnod_0363 | PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.714 |
Fnod_0721 | Fnod_0683 | Fnod_0721 | Fnod_0683 | PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase. | PFAM: ribonuclease H; KEGG: gfo:GFO_1824 RecD-like exodeoxyribonuclease. | 0.811 |
Fnod_0721 | mutL | Fnod_0721 | Fnod_1711 | PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.778 |
Fnod_0721 | polA | Fnod_0721 | Fnod_0360 | PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.799 |
Fnod_0721 | uvrA | Fnod_0721 | Fnod_1525 | PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.592 |