node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rcas_0198 | Rcas_0718 | Rcas_0198 | Rcas_0718 | KEGG: rrs:RoseRS_0091 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | PFAM: protein of unknown function DUF28; KEGG: rrs:RoseRS_4362 protein of unknown function DUF28. | 0.484 |
Rcas_0198 | mfd | Rcas_0198 | Rcas_1478 | KEGG: rrs:RoseRS_0091 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.573 |
Rcas_0198 | polA | Rcas_0198 | Rcas_1512 | KEGG: rrs:RoseRS_0091 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.673 |
Rcas_0198 | ruvA | Rcas_0198 | Rcas_1112 | KEGG: rrs:RoseRS_0091 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.571 |
Rcas_0198 | ruvB | Rcas_0198 | Rcas_3053 | KEGG: rrs:RoseRS_0091 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.498 |
Rcas_0198 | ruvC | Rcas_0198 | Rcas_0719 | KEGG: rrs:RoseRS_0091 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.475 |
Rcas_0361 | mfd | Rcas_0361 | Rcas_1478 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.693 |
Rcas_0361 | polA | Rcas_0361 | Rcas_1512 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.641 |
Rcas_0361 | ruvA | Rcas_0361 | Rcas_1112 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.589 |
Rcas_0361 | ruvB | Rcas_0361 | Rcas_3053 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.440 |
Rcas_0718 | Rcas_0198 | Rcas_0718 | Rcas_0198 | PFAM: protein of unknown function DUF28; KEGG: rrs:RoseRS_4362 protein of unknown function DUF28. | KEGG: rrs:RoseRS_0091 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. | 0.484 |
Rcas_0718 | aspS | Rcas_0718 | Rcas_3786 | PFAM: protein of unknown function DUF28; KEGG: rrs:RoseRS_4362 protein of unknown function DUF28. | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.834 |
Rcas_0718 | ruvA | Rcas_0718 | Rcas_1112 | PFAM: protein of unknown function DUF28; KEGG: rrs:RoseRS_4362 protein of unknown function DUF28. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.779 |
Rcas_0718 | ruvB | Rcas_0718 | Rcas_3053 | PFAM: protein of unknown function DUF28; KEGG: rrs:RoseRS_4362 protein of unknown function DUF28. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.400 |
Rcas_0718 | ruvC | Rcas_0718 | Rcas_0719 | PFAM: protein of unknown function DUF28; KEGG: rrs:RoseRS_4362 protein of unknown function DUF28. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.897 |
Rcas_1111 | Rcas_1113 | Rcas_1111 | Rcas_1113 | PFAM: NUDIX hydrolase; KEGG: rrs:RoseRS_3773 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | KEGG: rrs:RoseRS_3771 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | 0.524 |
Rcas_1111 | ruvA | Rcas_1111 | Rcas_1112 | PFAM: NUDIX hydrolase; KEGG: rrs:RoseRS_3773 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.795 |
Rcas_1113 | Rcas_1111 | Rcas_1113 | Rcas_1111 | KEGG: rrs:RoseRS_3771 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | PFAM: NUDIX hydrolase; KEGG: rrs:RoseRS_3773 NUDIX hydrolase; Belongs to the Nudix hydrolase family. | 0.524 |
Rcas_1113 | polA | Rcas_1113 | Rcas_1512 | KEGG: rrs:RoseRS_3771 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.752 |
Rcas_1113 | ruvA | Rcas_1113 | Rcas_1112 | KEGG: rrs:RoseRS_3771 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.593 |