node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | lwe1790 | lwe1782 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.992 |
purC | purE | lwe1790 | lwe1793 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase I; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | lwe1790 | lwe1786 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.996 |
purC | purH | lwe1790 | lwe1783 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.994 |
purC | purK | lwe1790 | lwe1792 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.996 |
purC | purL | lwe1790 | lwe1787 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.990 |
purC | purM | lwe1790 | lwe1785 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.994 |
purC | purN | lwe1790 | lwe1784 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.993 |
purC | purQ | lwe1790 | lwe1788 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.991 |
purC | purS | lwe1790 | lwe1789 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.989 |
purD | purC | lwe1782 | lwe1790 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | 0.992 |
purD | purE | lwe1782 | lwe1793 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase I; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purD | purF | lwe1782 | lwe1786 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.999 |
purD | purH | lwe1782 | lwe1783 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.996 |
purD | purK | lwe1782 | lwe1792 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.992 |
purD | purL | lwe1782 | lwe1787 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.990 |
purD | purM | lwe1782 | lwe1785 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.999 |
purD | purN | lwe1782 | lwe1784 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | lwe1782 | lwe1788 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.998 |
purD | purS | lwe1782 | lwe1789 | Phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.985 |