node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gpsB | lwe1618 | lwe1907 | lwe1618 | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Conserved hypothetical protein. | 0.655 |
gpsB | lwe1908 | lwe1907 | lwe1908 | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Conserved hypothetical protein; Belongs to the UPF0398 family. | 0.667 |
gpsB | lwe1909 | lwe1907 | lwe1909 | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Conserved hypothetical protein. | 0.643 |
gpsB | lwe1911 | lwe1907 | lwe1911 | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Penicillin-binding protein. | 0.892 |
gpsB | lwe1948 | lwe1907 | lwe1948 | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Conserved hypothetical protein. | 0.479 |
gpsB | lwe2231 | lwe1907 | lwe2231 | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | ABC transporter, permease protein. | 0.442 |
gpsB | recU | lwe1907 | lwe1910 | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.829 |
lwe0043 | lwe1908 | lwe0043 | lwe1908 | DHH subfamily 1 protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Conserved hypothetical protein; Belongs to the UPF0398 family. | 0.442 |
lwe0882 | lwe1908 | lwe0882 | lwe1908 | Conserved SprT family protein; Belongs to the SprT family. | Conserved hypothetical protein; Belongs to the UPF0398 family. | 0.520 |
lwe0882 | lwe1948 | lwe0882 | lwe1948 | Conserved SprT family protein; Belongs to the SprT family. | Conserved hypothetical protein. | 0.475 |
lwe0882 | lwe2231 | lwe0882 | lwe2231 | Conserved SprT family protein; Belongs to the SprT family. | ABC transporter, permease protein. | 0.552 |
lwe1618 | gpsB | lwe1618 | lwe1907 | Conserved hypothetical protein. | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.655 |
lwe1618 | lwe1908 | lwe1618 | lwe1908 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0398 family. | 0.458 |
lwe1618 | lwe1948 | lwe1618 | lwe1948 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.419 |
lwe1618 | lwe2231 | lwe1618 | lwe2231 | Conserved hypothetical protein. | ABC transporter, permease protein. | 0.734 |
lwe1908 | gpsB | lwe1908 | lwe1907 | Conserved hypothetical protein; Belongs to the UPF0398 family. | Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.667 |
lwe1908 | lwe0043 | lwe1908 | lwe0043 | Conserved hypothetical protein; Belongs to the UPF0398 family. | DHH subfamily 1 protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.442 |
lwe1908 | lwe0882 | lwe1908 | lwe0882 | Conserved hypothetical protein; Belongs to the UPF0398 family. | Conserved SprT family protein; Belongs to the SprT family. | 0.520 |
lwe1908 | lwe1618 | lwe1908 | lwe1618 | Conserved hypothetical protein; Belongs to the UPF0398 family. | Conserved hypothetical protein. | 0.458 |
lwe1908 | lwe1909 | lwe1908 | lwe1909 | Conserved hypothetical protein; Belongs to the UPF0398 family. | Conserved hypothetical protein. | 0.828 |