STRINGSTRING
minC minC minD minD minE minE mreD mreD mreC mreC ftsZ ftsZ ABK61987.1 ABK61987.1 ABK60750.1 ABK60750.1 rodA rodA ABK60535.1 ABK60535.1 ABK62103.1 ABK62103.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (210 aa)    
Predicted Functional Partners:
minD
Septum site-determining protein MinD; Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968.
 
 
 0.999
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
  
 0.960
mreD
Rod shape-determining protein MreD; Identified by match to protein family HMM PF04093.
 
  
 0.934
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.932
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.906
ABK61987.1
Rod shape-determining protein mreB; Identified by match to protein family HMM PF06723; match to protein family HMM TIGR00904.
  
  
 0.747
ABK60750.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.732
rodA
Rod shape-determining protein RodA; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210; Belongs to the SEDS family.
     
 0.720
ABK60535.1
Penicillin-binding protein 2; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.
  
  
 0.684
ABK62103.1
DNA repair protein; Identified by match to protein family HMM PF00633; match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
  
  
 0.679
Your Current Organism:
Clostridium novyi
NCBI taxonomy Id: 386415
Other names: C. novyi NT, Clostridium novyi NT, Clostridium novyi str. NT, Clostridium novyi strain NT, Clostridium novyi-NT
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