node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LVIS_0785 | fmt | LVIS_0785 | LVIS_0965 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.921 |
LVIS_0785 | glyA | LVIS_0785 | LVIS_1287 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.988 |
LVIS_0960 | LVIS_0962 | LVIS_0960 | LVIS_0962 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | 0.754 |
LVIS_0960 | LVIS_0963 | LVIS_0960 | LVIS_0963 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Serine/threonine protein phosphatase. | 0.649 |
LVIS_0960 | LVIS_0964 | LVIS_0960 | LVIS_0964 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | tRNA and rRNA cytosine-C5-methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.839 |
LVIS_0960 | LVIS_0967 | LVIS_0960 | LVIS_0967 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.625 |
LVIS_0960 | fmt | LVIS_0960 | LVIS_0965 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.820 |
LVIS_0960 | folD | LVIS_0960 | LVIS_0978 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.635 |
LVIS_0960 | priA | LVIS_0960 | LVIS_0966 | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.607 |
LVIS_0962 | LVIS_0960 | LVIS_0962 | LVIS_0960 | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.754 |
LVIS_0962 | LVIS_0963 | LVIS_0962 | LVIS_0963 | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | Serine/threonine protein phosphatase. | 0.999 |
LVIS_0962 | LVIS_0964 | LVIS_0962 | LVIS_0964 | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | tRNA and rRNA cytosine-C5-methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.870 |
LVIS_0962 | LVIS_0967 | LVIS_0962 | LVIS_0967 | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.780 |
LVIS_0962 | fmt | LVIS_0962 | LVIS_0965 | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.846 |
LVIS_0962 | priA | LVIS_0962 | LVIS_0966 | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.783 |
LVIS_0963 | LVIS_0960 | LVIS_0963 | LVIS_0960 | Serine/threonine protein phosphatase. | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.649 |
LVIS_0963 | LVIS_0962 | LVIS_0963 | LVIS_0962 | Serine/threonine protein phosphatase. | Serine/threonine protein kinase with beta-lactam (PASTA) domains. | 0.999 |
LVIS_0963 | LVIS_0964 | LVIS_0963 | LVIS_0964 | Serine/threonine protein phosphatase. | tRNA and rRNA cytosine-C5-methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.959 |
LVIS_0963 | LVIS_0967 | LVIS_0963 | LVIS_0967 | Serine/threonine protein phosphatase. | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.813 |
LVIS_0963 | fmt | LVIS_0963 | LVIS_0965 | Serine/threonine protein phosphatase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.932 |