STRINGSTRING
thiC thiC Smal_1505 Smal_1505 thiG thiG thiE thiE Smal_0612 Smal_0612 Smal_1666 Smal_1666 Smal_3189 Smal_3189 purM purM purK purK hfq hfq Smal_3324 Smal_3324
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (614 aa)    
Predicted Functional Partners:
Smal_1505
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: xcb:XC_2499 phosphomethylpyrimidine kinase.
 
 
 0.993
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.969
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.938
Smal_0612
TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; thiamine monophosphate synthase; KEGG: xom:XOO_3593 hypothetical protein.
  
  
 0.881
Smal_1666
PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: xcv:XCV2074 molybdopterin biosynthesis protein MoeB.
 
  
 0.876
Smal_3189
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: xcv:XCV3416 sulfur carrier protein ThiS.
  
  
 0.875
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: xac:XAC2959 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
     
 0.807
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
     
  0.800
hfq
RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
      
 0.581
Smal_3324
PFAM: Ion transport 2 domain protein; KEGG: aby:ABAYE0189 hypothetical protein.
       0.572
Your Current Organism:
Stenotrophomonas maltophilia R5513
NCBI taxonomy Id: 391008
Other names: S. maltophilia R551-3, Stenotrophomonas maltophilia R551-3, Stenotrophomonas maltophilia str. R551-3, Stenotrophomonas maltophilia strain R551-3
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