STRINGSTRING
cyaY cyaY Veis_2374 Veis_2374 iscS iscS Veis_2991 Veis_2991 Veis_2990 Veis_2990 hscB hscB Veis_2378 Veis_2378 hscA hscA hemH hemH Veis_1801 Veis_1801 rpsI rpsI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cyaYFrataxin family protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (109 aa)    
Predicted Functional Partners:
Veis_2374
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.979
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 0.966
Veis_2991
PFAM: nitrogen-fixing NifU domain protein; KEGG: plu:plu4673 hypothetical protein.
  
 
 0.966
Veis_2990
PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: plu:plu4674 hypothetical protein.
   
 0.953
hscB
Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.863
Veis_2378
TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: rfr:Rfer_2182 ferredoxin, 2Fe-2S type.
  
 
 0.826
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 
 0.710
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 
 0.655
Veis_1801
KEGG: pol:Bpro_2582 protein-methionine-S-oxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Belongs to the MsrB Met sulfoxide reductase family.
    
 
 0.640
rpsI
PFAM: ribosomal protein S9; KEGG: pol:Bpro_4112 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
   0.605
Your Current Organism:
Verminephrobacter eiseniae
NCBI taxonomy Id: 391735
Other names: V. eiseniae EF01-2, Verminephrobacter eiseniae EF01-2, Verminephrobacter eiseniae str. EF01-2, Verminephrobacter eiseniae strain EF01-2
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