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fabZ fabZ lpxA lpxA lpxD lpxD acpP acpP Aave_2051 Aave_2051 Aave_3255 Aave_3255 Aave_1185 Aave_1185 Aave_1184 Aave_1184 Aave_4181 Aave_4181 lpxC lpxC Aave_1187 Aave_1187
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)    
Predicted Functional Partners:
lpxA
acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
 0.993
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
  
 0.972
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
 
 0.969
Aave_2051
Enoyl-[acyl-carrier-protein] reductase (NADH); PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bcn:Bcen_3497 short-chain dehydrogenase/reductase SDR.
 
 
 0.967
Aave_3255
Enoyl-[acyl-carrier-protein] reductase (NADH); PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pol:Bpro_2419 short-chain dehydrogenase/reductase SDR.
 
 
 0.965
Aave_1185
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.957
Aave_1184
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: pol:Bpro_3648 malonyl CoA-acyl carrier protein transacylase.
 
  
 0.948
Aave_4181
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
 
 0.946
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
    
 0.937
Aave_1187
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.934
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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