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panB panB panC panC Aave_1400 Aave_1400 ilvE ilvE Aave_0260 Aave_0260 Aave_4737 Aave_4737 ilvD ilvD Aave_3851 Aave_3851 ribB ribB Aave_3849 Aave_3849 Aave_3555 Aave_3555
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (296 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.999
Aave_1400
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
 0.975
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.919
Aave_0260
Ketopantoate reductase; KEGG: pol:Bpro_0197 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein.
    
 0.916
Aave_4737
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.916
ilvD
KEGG: reu:Reut_A2432 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
     
 0.908
Aave_3851
KEGG: pol:Bpro_0902 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
     0.862
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 
  
 0.730
Aave_3849
TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: pol:Bpro_0904 para-aminobenzoate synthase, component I.
 
   
 0.717
Aave_3555
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
   
 0.667
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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