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cobB cobB Cmaq_0276 Cmaq_0276 Cmaq_1647 Cmaq_1647 nadE nadE nadK nadK Cmaq_1331 Cmaq_1331 Cmaq_0204 Cmaq_0204 Cmaq_1949 Cmaq_1949 Cmaq_0256 Cmaq_0256 Cmaq_1956 Cmaq_1956 Cmaq_0488 Cmaq_0488
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cobBSilent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (257 aa)    
Predicted Functional Partners:
Cmaq_0276
TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: pis:Pisl_0898 cytidyltransferase-related domain.
   
 
  0.959
Cmaq_1647
TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase; KEGG: pis:Pisl_1561 nicotinamide-nucleotide adenylyltransferase.
   
 
  0.959
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.939
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.925
Cmaq_1331
ATP-NAD/AcoX kinase; PFAM: regulatory protein ArsR; ATP-NAD/AcoX kinase; KEGG: pai:PAE3116 hypothetical protein.
  
 
 0.925
Cmaq_0204
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: pai:PAE1996 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.830
Cmaq_1949
PFAM: histone deacetylase superfamily; KEGG: pis:Pisl_0381 histone deacetylase superfamily.
   
 
 0.749
Cmaq_0256
TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: pis:Pisl_0270 acetate--CoA ligase.
   
 0.744
Cmaq_1956
Putative transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein; KEGG: pis:Pisl_1563 putative transcriptional regulator, CopG family.
   
    0.638
Cmaq_0488
TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; KEGG: pis:Pisl_0380 ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 
 0.615
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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