node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Glov_2470 | Glov_2765 | Glov_2470 | Glov_2765 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.913 |
Glov_2765 | Glov_2470 | Glov_2765 | Glov_2470 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | 0.913 |
Glov_2765 | Glov_2766 | Glov_2765 | Glov_2766 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | 0.789 |
Glov_2765 | Glov_2923 | Glov_2765 | Glov_2923 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: ppd:Ppro_2900 heavy metal translocating P-type ATPase. | 0.441 |
Glov_2765 | birA | Glov_2765 | Glov_1317 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.462 |
Glov_2765 | hfq | Glov_2765 | Glov_0991 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.447 |
Glov_2765 | hrcA | Glov_2765 | Glov_2831 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.400 |
Glov_2765 | thiC | Glov_2765 | Glov_2764 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.486 |
Glov_2765 | thiE-2 | Glov_2765 | Glov_2763 | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.528 |
Glov_2766 | Glov_2765 | Glov_2766 | Glov_2765 | TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.789 |
Glov_2766 | thiC | Glov_2766 | Glov_2764 | TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.468 |
Glov_2766 | thiE-2 | Glov_2766 | Glov_2763 | TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. | Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.497 |
Glov_2923 | Glov_2765 | Glov_2923 | Glov_2765 | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: ppd:Ppro_2900 heavy metal translocating P-type ATPase. | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.441 |
Glov_2923 | birA | Glov_2923 | Glov_1317 | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: ppd:Ppro_2900 heavy metal translocating P-type ATPase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.500 |
birA | Glov_2765 | Glov_1317 | Glov_2765 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.462 |
birA | Glov_2923 | Glov_1317 | Glov_2923 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: ppd:Ppro_2900 heavy metal translocating P-type ATPase. | 0.500 |
birA | hfq | Glov_1317 | Glov_0991 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.465 |
birA | hrcA | Glov_1317 | Glov_2831 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.536 |
birA | thiE-2 | Glov_1317 | Glov_2763 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.562 |
hfq | Glov_2765 | Glov_0991 | Glov_2765 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Putative transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. | 0.447 |