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nfo nfo Spro_2715 Spro_2715 nth nth Spro_3226 Spro_3226 maiA maiA Spro_2310 Spro_2310 Spro_2311 Spro_2311 ung ung Spro_3547 Spro_3547 polA polA Spro_3472 Spro_3472
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. (279 aa)    
Predicted Functional Partners:
Spro_2715
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ypi:YpsIP31758_1976 exodeoxyribonuclease III.
    
 
 0.794
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.788
Spro_3226
PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_2674 hypothetical protein; Belongs to the UPF0324 family.
       0.541
maiA
Asp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
      
 0.537
Spro_2310
PFAM: alpha/beta hydrolase fold; KEGG: ppu:PP_3943 hydrolase, alpha/beta fold family.
      
 0.537
Spro_2311
PFAM: monooxygenase FAD-binding; KEGG: ppf:Pput_1893 monooxygenase, FAD-binding.
      
 0.537
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 
 0.530
Spro_3547
PFAM: helix-turn-helix- domain containing protein AraC type; HhH-GPD family protein; Ada metal-binding domain protein; AlkA domain protein; KEGG: reh:H16_B2551 DNA-3-methyladenine glycosylase II, adenosine deaminase.
   
 
 0.503
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.430
Spro_3472
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: yen:YE1162 NADP-dependent malic enzyme.
     
 0.408
Your Current Organism:
Serratia proteamaculans
NCBI taxonomy Id: 399741
Other names: S. proteamaculans 568, Serratia proteamaculans 568, Serratia proteamaculans str. 568, Serratia proteamaculans strain 568
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