node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_0793 | Spro_1695 | Spro_0793 | Spro_1695 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | 0.902 |
Spro_0793 | ndk | Spro_0793 | Spro_3613 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
Spro_0793 | pyrF | Spro_0793 | Spro_2647 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.900 |
Spro_0793 | pyrH | Spro_0793 | Spro_3788 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
Spro_0793 | surE | Spro_0793 | Spro_0829 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | Stationary-phase survival protein SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.905 |
Spro_0793 | udk | Spro_0793 | Spro_1576 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: yen:YE2783 uridine kinase. | 0.903 |
Spro_0793 | upp | Spro_0793 | Spro_3523 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.902 |
Spro_1695 | Spro_0793 | Spro_1695 | Spro_0793 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | 0.902 |
Spro_1695 | pyrF | Spro_1695 | Spro_2647 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.930 |
Spro_1695 | pyrH | Spro_1695 | Spro_3788 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.954 |
Spro_1695 | rpsB | Spro_1695 | Spro_3790 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | PFAM: ribosomal protein S2; KEGG: ypi:YpsIP31758_1013 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.497 |
Spro_1695 | surE | Spro_1695 | Spro_0829 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | Stationary-phase survival protein SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. | 0.909 |
Spro_1695 | tsf | Spro_1695 | Spro_3789 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.471 |
Spro_1695 | udk | Spro_1695 | Spro_1576 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: yen:YE2783 uridine kinase. | 0.996 |
Spro_1695 | upp | Spro_1695 | Spro_3523 | PFAM: phosphoribosyltransferase; KEGG: plu:plu2180 hypothetical protein. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.923 |
frr | ndk | Spro_3787 | Spro_3613 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.710 |
frr | pyrH | Spro_3787 | Spro_3788 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.973 |
frr | rpsB | Spro_3787 | Spro_3790 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | PFAM: ribosomal protein S2; KEGG: ypi:YpsIP31758_1013 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.986 |
frr | tsf | Spro_3787 | Spro_3789 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.984 |
ndk | Spro_0793 | Spro_3613 | Spro_0793 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: ypi:YpsIP31758_3318 MazG family protein. | 0.900 |