node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_2176 | rlmM | Spro_2176 | Spro_3803 | PFAM: FAD linked oxidase domain protein; KEGG: yen:YE2174 hypothetical protein. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.452 |
Spro_3255 | rlmM | Spro_3255 | Spro_3803 | PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.598 |
Spro_3255 | yihI | Spro_3255 | Spro_4885 | PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein. | Protein of unknown function DUF414; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.670 |
Spro_3804 | Spro_3805 | Spro_3804 | Spro_3805 | PFAM: protein of unknown function DUF423; KEGG: yen:YE3299 hypothetical protein. | Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0999 glycine cleavage system transcriptional activator. | 0.692 |
Spro_3804 | rlmM | Spro_3804 | Spro_3803 | PFAM: protein of unknown function DUF423; KEGG: yen:YE3299 hypothetical protein. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.903 |
Spro_3805 | Spro_3804 | Spro_3805 | Spro_3804 | Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0999 glycine cleavage system transcriptional activator. | PFAM: protein of unknown function DUF423; KEGG: yen:YE3299 hypothetical protein. | 0.692 |
Spro_3805 | rlmM | Spro_3805 | Spro_3803 | Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0999 glycine cleavage system transcriptional activator. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.643 |
Spro_3808 | rlmM | Spro_3808 | Spro_3803 | PFAM: Fe-S metabolism associated SufE; KEGG: yps:YPTB3019 hypothetical protein. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.452 |
Spro_4409 | ftsL | Spro_4409 | Spro_0754 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.668 |
Spro_4409 | rlmM | Spro_4409 | Spro_3803 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.415 |
Spro_4577 | rlmM | Spro_4577 | Spro_3803 | PFAM: protein of unknown function UPF0270; KEGG: yen:YE3952 hypothetical protein; Belongs to the UPF0270 family. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.420 |
ftsL | Spro_4409 | Spro_0754 | Spro_4409 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.668 |
ftsL | rlmM | Spro_0754 | Spro_3803 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.413 |
nfuA | rlmM | Spro_4634 | Spro_3803 | HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.536 |
rlmM | Spro_2176 | Spro_3803 | Spro_2176 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | PFAM: FAD linked oxidase domain protein; KEGG: yen:YE2174 hypothetical protein. | 0.452 |
rlmM | Spro_3255 | Spro_3803 | Spro_3255 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein. | 0.598 |
rlmM | Spro_3804 | Spro_3803 | Spro_3804 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | PFAM: protein of unknown function DUF423; KEGG: yen:YE3299 hypothetical protein. | 0.903 |
rlmM | Spro_3805 | Spro_3803 | Spro_3805 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0999 glycine cleavage system transcriptional activator. | 0.643 |
rlmM | Spro_3808 | Spro_3803 | Spro_3808 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | PFAM: Fe-S metabolism associated SufE; KEGG: yps:YPTB3019 hypothetical protein. | 0.452 |
rlmM | Spro_4409 | Spro_3803 | Spro_4409 | Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.415 |