node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_4029 | Spro_4030 | Spro_4029 | Spro_4030 | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.614 |
Spro_4029 | Spro_4032 | Spro_4029 | Spro_4032 | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | 0.517 |
Spro_4029 | Spro_4033 | Spro_4029 | Spro_4033 | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | PFAM: protein of unknown function DUF167; KEGG: yen:YE3436 hypothetical protein; Belongs to the UPF0235 family. | 0.517 |
Spro_4029 | Spro_4034 | Spro_4029 | Spro_4034 | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.494 |
Spro_4029 | Spro_4035 | Spro_4029 | Spro_4035 | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.494 |
Spro_4029 | proC | Spro_4029 | Spro_4031 | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.575 |
Spro_4030 | Spro_4029 | Spro_4030 | Spro_4029 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | 0.614 |
Spro_4030 | Spro_4032 | Spro_4030 | Spro_4032 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | 0.872 |
Spro_4030 | Spro_4033 | Spro_4030 | Spro_4033 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | PFAM: protein of unknown function DUF167; KEGG: yen:YE3436 hypothetical protein; Belongs to the UPF0235 family. | 0.744 |
Spro_4030 | Spro_4034 | Spro_4030 | Spro_4034 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.713 |
Spro_4030 | Spro_4035 | Spro_4030 | Spro_4035 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.720 |
Spro_4030 | proC | Spro_4030 | Spro_4031 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.839 |
Spro_4032 | Spro_4029 | Spro_4032 | Spro_4029 | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | 0.517 |
Spro_4032 | Spro_4030 | Spro_4032 | Spro_4030 | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.872 |
Spro_4032 | Spro_4033 | Spro_4032 | Spro_4033 | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | PFAM: protein of unknown function DUF167; KEGG: yen:YE3436 hypothetical protein; Belongs to the UPF0235 family. | 0.832 |
Spro_4032 | Spro_4034 | Spro_4032 | Spro_4034 | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.760 |
Spro_4032 | Spro_4035 | Spro_4032 | Spro_4035 | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.752 |
Spro_4032 | proC | Spro_4032 | Spro_4031 | PFAM: protein of unknown function YGGT; KEGG: yen:YE3435 hypothetical protein. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.768 |
Spro_4033 | Spro_4029 | Spro_4033 | Spro_4029 | PFAM: protein of unknown function DUF167; KEGG: yen:YE3436 hypothetical protein; Belongs to the UPF0235 family. | TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: eca:ECA3626 putative type II/IV secretion system protein. | 0.517 |
Spro_4033 | Spro_4030 | Spro_4033 | Spro_4030 | PFAM: protein of unknown function DUF167; KEGG: yen:YE3436 hypothetical protein; Belongs to the UPF0235 family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | 0.744 |