node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_1205 | Spro_4044 | Spro_1205 | Spro_4044 | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.685 |
Spro_1205 | Spro_4346 | Spro_1205 | Spro_4346 | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | PFAM: Stringent starvation protein B; KEGG: ecv:APECO1_3216 stringent starvation protein B. | 0.742 |
Spro_1205 | bamE | Spro_1205 | Spro_3687 | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.752 |
Spro_1205 | cca | Spro_1205 | Spro_4293 | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.642 |
Spro_1205 | ftsB | Spro_1205 | Spro_0825 | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.699 |
Spro_1205 | ftsQ | Spro_1205 | Spro_0764 | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.692 |
Spro_1205 | secE | Spro_1205 | Spro_0271 | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.676 |
Spro_4043 | Spro_4044 | Spro_4043 | Spro_4044 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | 0.814 |
Spro_4043 | mltC | Spro_4043 | Spro_4045 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.651 |
Spro_4043 | trmB | Spro_4043 | Spro_4042 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.609 |
Spro_4044 | Spro_1205 | Spro_4044 | Spro_1205 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | KEGG: yps:YPTB1101 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta. | 0.685 |
Spro_4044 | Spro_4043 | Spro_4044 | Spro_4043 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.814 |
Spro_4044 | Spro_4346 | Spro_4044 | Spro_4346 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | PFAM: Stringent starvation protein B; KEGG: ecv:APECO1_3216 stringent starvation protein B. | 0.725 |
Spro_4044 | bamE | Spro_4044 | Spro_3687 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.656 |
Spro_4044 | cca | Spro_4044 | Spro_4293 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.669 |
Spro_4044 | ftsB | Spro_4044 | Spro_0825 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.698 |
Spro_4044 | ftsQ | Spro_4044 | Spro_0764 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.659 |
Spro_4044 | mltC | Spro_4044 | Spro_4045 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Lytic transglycosylase catalytic; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.688 |
Spro_4044 | secE | Spro_4044 | Spro_0271 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.631 |
Spro_4044 | trmB | Spro_4044 | Spro_4042 | Protein-tyrosine-phosphatase; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.581 |