node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Spro_4313 | Spro_4315 | Spro_4313 | Spro_4315 | PFAM: plasmid maintenance system killer; KEGG: vco:VC0395_0930 putative killer protein. | PFAM: protein of unknown function DUF45; KEGG: yen:YE3701 hypothetical protein. | 0.743 |
Spro_4313 | Spro_4316 | Spro_4313 | Spro_4316 | PFAM: plasmid maintenance system killer; KEGG: vco:VC0395_0930 putative killer protein. | PFAM: oxidoreductase domain protein; KEGG: yen:YE3702 putative MocA-family oxidoreductase. | 0.585 |
Spro_4313 | rlmG | Spro_4313 | Spro_4312 | PFAM: plasmid maintenance system killer; KEGG: vco:VC0395_0930 putative killer protein. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.410 |
Spro_4315 | Spro_4313 | Spro_4315 | Spro_4313 | PFAM: protein of unknown function DUF45; KEGG: yen:YE3701 hypothetical protein. | PFAM: plasmid maintenance system killer; KEGG: vco:VC0395_0930 putative killer protein. | 0.743 |
Spro_4315 | Spro_4316 | Spro_4315 | Spro_4316 | PFAM: protein of unknown function DUF45; KEGG: yen:YE3701 hypothetical protein. | PFAM: oxidoreductase domain protein; KEGG: yen:YE3702 putative MocA-family oxidoreductase. | 0.620 |
Spro_4315 | rlmG | Spro_4315 | Spro_4312 | PFAM: protein of unknown function DUF45; KEGG: yen:YE3701 hypothetical protein. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.560 |
Spro_4316 | Spro_4313 | Spro_4316 | Spro_4313 | PFAM: oxidoreductase domain protein; KEGG: yen:YE3702 putative MocA-family oxidoreductase. | PFAM: plasmid maintenance system killer; KEGG: vco:VC0395_0930 putative killer protein. | 0.585 |
Spro_4316 | Spro_4315 | Spro_4316 | Spro_4315 | PFAM: oxidoreductase domain protein; KEGG: yen:YE3702 putative MocA-family oxidoreductase. | PFAM: protein of unknown function DUF45; KEGG: yen:YE3701 hypothetical protein. | 0.620 |
Spro_4316 | rlmG | Spro_4316 | Spro_4312 | PFAM: oxidoreductase domain protein; KEGG: yen:YE3702 putative MocA-family oxidoreductase. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.416 |
obg | rlmG | Spro_0476 | Spro_4312 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.484 |
obg | rplA | Spro_0476 | Spro_0274 | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.878 |
rapA | rlmG | Spro_0730 | Spro_4312 | SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.488 |
rlmG | Spro_4313 | Spro_4312 | Spro_4313 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | PFAM: plasmid maintenance system killer; KEGG: vco:VC0395_0930 putative killer protein. | 0.410 |
rlmG | Spro_4315 | Spro_4312 | Spro_4315 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | PFAM: protein of unknown function DUF45; KEGG: yen:YE3701 hypothetical protein. | 0.560 |
rlmG | Spro_4316 | Spro_4312 | Spro_4316 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | PFAM: oxidoreductase domain protein; KEGG: yen:YE3702 putative MocA-family oxidoreductase. | 0.416 |
rlmG | obg | Spro_4312 | Spro_0476 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.484 |
rlmG | rapA | Spro_4312 | Spro_0730 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.488 |
rlmG | rlmL | Spro_4312 | Spro_1743 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.447 |
rlmG | rplA | Spro_4312 | Spro_0274 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.402 |
rlmG | rsmB | Spro_4312 | Spro_4513 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.412 |