node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rpic_0002 | Rpic_0042 | Rpic_0002 | Rpic_0042 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: rso:RSc0140 putative exodeoxyribonuclease III protein; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | 0.758 |
Rpic_0002 | Rpic_1952 | Rpic_0002 | Rpic_1952 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rso:RSc1593 probable exodeoxyribonuclease III protein. | 0.758 |
Rpic_0002 | ung | Rpic_0002 | Rpic_3129 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.787 |
Rpic_0042 | Rpic_0002 | Rpic_0042 | Rpic_0002 | KEGG: rso:RSc0140 putative exodeoxyribonuclease III protein; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.758 |
Rpic_0042 | Rpic_1952 | Rpic_0042 | Rpic_1952 | KEGG: rso:RSc0140 putative exodeoxyribonuclease III protein; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rso:RSc1593 probable exodeoxyribonuclease III protein. | 0.929 |
Rpic_0042 | nth | Rpic_0042 | Rpic_0871 | KEGG: rso:RSc0140 putative exodeoxyribonuclease III protein; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.973 |
Rpic_0042 | ung | Rpic_0042 | Rpic_3129 | KEGG: rso:RSc0140 putative exodeoxyribonuclease III protein; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.669 |
Rpic_1952 | Rpic_0002 | Rpic_1952 | Rpic_0002 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rso:RSc1593 probable exodeoxyribonuclease III protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.758 |
Rpic_1952 | Rpic_0042 | Rpic_1952 | Rpic_0042 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rso:RSc1593 probable exodeoxyribonuclease III protein. | KEGG: rso:RSc0140 putative exodeoxyribonuclease III protein; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase. | 0.929 |
Rpic_1952 | nth | Rpic_1952 | Rpic_0871 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rso:RSc1593 probable exodeoxyribonuclease III protein. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.756 |
Rpic_1952 | ung | Rpic_1952 | Rpic_3129 | TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rso:RSc1593 probable exodeoxyribonuclease III protein. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.669 |
Rpic_3124 | Rpic_3125 | Rpic_3124 | Rpic_3125 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rso:RSc2882 anthranilate synthase component II. | KEGG: rso:RSc2883 putative signal peptide protein. | 0.773 |
Rpic_3124 | Rpic_3128 | Rpic_3124 | Rpic_3128 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rso:RSc2882 anthranilate synthase component II. | PFAM: adenylate cyclase; KEGG: rso:RSc2886 hypothetical protein. | 0.718 |
Rpic_3124 | trpC | Rpic_3124 | Rpic_3127 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rso:RSc2882 anthranilate synthase component II. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: rso:RSc2885 probable indole-3-glycerol phosphate synthase protein; Belongs to the TrpC family. | 0.999 |
Rpic_3124 | trpD | Rpic_3124 | Rpic_3126 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rso:RSc2882 anthranilate synthase component II. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
Rpic_3124 | trpE | Rpic_3124 | Rpic_3123 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rso:RSc2882 anthranilate synthase component II. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
Rpic_3124 | ung | Rpic_3124 | Rpic_3129 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rso:RSc2882 anthranilate synthase component II. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.750 |
Rpic_3125 | Rpic_3124 | Rpic_3125 | Rpic_3124 | KEGG: rso:RSc2883 putative signal peptide protein. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rso:RSc2882 anthranilate synthase component II. | 0.773 |
Rpic_3125 | Rpic_3128 | Rpic_3125 | Rpic_3128 | KEGG: rso:RSc2883 putative signal peptide protein. | PFAM: adenylate cyclase; KEGG: rso:RSc2886 hypothetical protein. | 0.716 |
Rpic_3125 | trpC | Rpic_3125 | Rpic_3127 | KEGG: rso:RSc2883 putative signal peptide protein. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: rso:RSc2885 probable indole-3-glycerol phosphate synthase protein; Belongs to the TrpC family. | 0.741 |