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psmB1 psmB1 psmB2 psmB2 pan pan nfi nfi psmA psmA Hbut_0579 Hbut_0579 Hbut_0799 Hbut_0799 Hbut_0300 Hbut_0300 Hbut_1358 Hbut_1358 Hbut_0481 Hbut_0481 Hbut_0918 Hbut_0918
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
psmB1Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (204 aa)    
Predicted Functional Partners:
psmB2
Proteasome beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
  
 
0.905
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
  
 0.877
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.856
psmA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.827
Hbut_0579
50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.755
Hbut_0799
Predicted ATPase.
 
 0.645
Hbut_0300
ATPases of AAA+ class, SpoVK, putative cell division.
  
 0.586
Hbut_1358
ATP-dependent protease.
  
 0.586
Hbut_0481
Thermosome beta subunit; Belongs to the TCP-1 chaperonin family.
 
 
 0.577
Hbut_0918
Thermosome alpha subunit; Belongs to the TCP-1 chaperonin family.
 
 
 0.566
Your Current Organism:
Hyperthermus butylicus
NCBI taxonomy Id: 415426
Other names: H. butylicus DSM 5456, Hyperthermus butylicus DSM 5456, Hyperthermus butylicus str. DSM 5456, Hyperthermus butylicus strain DSM 5456
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