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lpcA lpcA hldE hldE gmhB gmhB gmhA gmhA rfaF rfaF hisB hisB hldD hldD ksgA ksgA lgtF lgtF tyrR tyrR sapC sapC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
lpcAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (194 aa)    
Predicted Functional Partners:
hldE
Bifunctional protein HldE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
  
 0.988
gmhB
D,D-heptose 1,7-bisphosphate phosphatase.
  
 0.987
gmhA
Putative phosphoheptose isomerase.
  
  
 
0.925
rfaF
ADP-heptose:LPS heptosyltransferase II.
 
   
 0.704
hisB
Histidine biosynthesis bifunctional protein hisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
  
  
 0.648
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
 
  
 0.639
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
   
  
 0.560
lgtF
UDP-glucose--lipooligosaccharide glucosyltransferase.
 
 
 
 0.540
tyrR
Transcriptional regulatory protein TyrR.
       0.491
sapC
Peptide transport system permease protein SapC.
       0.490
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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