STRINGSTRING
thrB thrB AZC_1848 AZC_1848 AZC_2239 AZC_2239 ilvE ilvE ispH ispH AZC_4341 AZC_4341 AZC_2180 AZC_2180 ahcY ahcY AZC_1584 AZC_1584 AZC_3050 AZC_3050 AZC_3388 AZC_3388
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (321 aa)    
Predicted Functional Partners:
AZC_1848
Homoserine dehydrogenase.
 
  
 0.935
AZC_2239
Threonine synthase.
    
 0.923
ilvE
Branched-chain amino acid aminotransferase I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.818
ispH
LytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.814
AZC_4341
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.812
AZC_2180
O-acetylhomoserine/O-acetylserine sulfhydrylase.
    
  0.806
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.804
AZC_1584
Cystathionine beta-lyase.
     
  0.800
AZC_3050
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
AZC_3388
Serine O-acetyltransferase.
     
  0.800
Your Current Organism:
Azorhizobium caulinodans
NCBI taxonomy Id: 438753
Other names: A. caulinodans ORS 571, Azorhizobium caulinodans ORS 571, Azorhizobium caulinodans str. ORS 571, Azorhizobium caulinodans strain ORS 571, Rhizobium sp. ORS 571
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