node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GM21_1226 | GM21_1902 | GM21_1226 | GM21_1902 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: gbm:Gbem_2321 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.547 |
GM21_1226 | bioB | GM21_1226 | GM21_2164 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.523 |
GM21_1226 | gmk | GM21_1226 | GM21_1050 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.591 |
GM21_1226 | nadA | GM21_1226 | GM21_3588 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.600 |
GM21_1902 | GM21_1226 | GM21_1902 | GM21_1226 | KEGG: gbm:Gbem_2321 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.547 |
GM21_1902 | GM21_2336 | GM21_1902 | GM21_2336 | KEGG: gbm:Gbem_2321 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.997 |
GM21_1902 | bioB | GM21_1902 | GM21_2164 | KEGG: gbm:Gbem_2321 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.438 |
GM21_1902 | nadA | GM21_1902 | GM21_3588 | KEGG: gbm:Gbem_2321 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.998 |
GM21_2336 | GM21_1902 | GM21_2336 | GM21_1902 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | KEGG: gbm:Gbem_2321 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.997 |
GM21_2336 | nadA | GM21_2336 | GM21_3588 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.999 |
GM21_2468 | GM21_2569 | GM21_2468 | GM21_2569 | KEGG: gbm:Gbem_1779 transferase hexapeptide repeat containing protein. | TIGRFAM: serine O-acetyltransferase; KEGG: gbm:Gbem_1644 serine O-acetyltransferase. | 0.920 |
GM21_2468 | nadA | GM21_2468 | GM21_3588 | KEGG: gbm:Gbem_1779 transferase hexapeptide repeat containing protein. | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.766 |
GM21_2569 | GM21_2468 | GM21_2569 | GM21_2468 | TIGRFAM: serine O-acetyltransferase; KEGG: gbm:Gbem_1644 serine O-acetyltransferase. | KEGG: gbm:Gbem_1779 transferase hexapeptide repeat containing protein. | 0.920 |
GM21_2569 | nadA | GM21_2569 | GM21_3588 | TIGRFAM: serine O-acetyltransferase; KEGG: gbm:Gbem_1644 serine O-acetyltransferase. | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.766 |
GM21_3589 | nadA | GM21_3589 | GM21_3588 | KEGG: gbm:Gbem_3520 carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein. | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.670 |
GM21_3589 | tatA-6 | GM21_3589 | GM21_3587 | KEGG: gbm:Gbem_3520 carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein. | Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.408 |
bioB | GM21_1226 | GM21_2164 | GM21_1226 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.523 |
bioB | GM21_1902 | GM21_2164 | GM21_1902 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | KEGG: gbm:Gbem_2321 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. | 0.438 |
bioB | nadA | GM21_2164 | GM21_3588 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.591 |
gmk | GM21_1226 | GM21_1050 | GM21_1226 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.591 |