STRINGSTRING
ung ung polA polA Aasi_0152 Aasi_0152 rpsR rpsR nth nth rpsF rpsF rplI rplI Aasi_0301 Aasi_0301 dut dut tadA tadA Aasi_0401 Aasi_0401
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ungHypothetical protein; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (220 aa)    
Predicted Functional Partners:
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.785
Aasi_0152
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.680
rpsR
Hypothetical protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.630
nth
Hypothetical protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
  
 
 0.621
rpsF
Hypothetical protein; Binds together with S18 to 16S ribosomal RNA.
       0.616
rplI
Hypothetical protein; Binds to the 23S rRNA.
       0.609
Aasi_0301
Hypothetical protein; PFAM: PF07977, Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ;PF03331, UDP-3-O-acyl N-acetylglucosamine deacetylase; PRODOM: PD011499, UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal; GENE3D: G3DSA:3.30.230.20, UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal;G3DSA:3.30.1700.10, UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal; TIGRFAMS: TIGR01750, Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ;TIGR00325, UDP-3-O-acyl N-acetylglucosamine deacetylase; Belongs to the CinA family.
     
 0.493
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.482
tadA
Hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
 
 0.479
Aasi_0401
PFAM: PF03811, Insertion element protein; SUPERFAMILY: SSF46689, Homeodomain-like.
       0.446
Your Current Organism:
Amoebophilus asiaticus
NCBI taxonomy Id: 452471
Other names: C. Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus 5a2, Candidatus Amoebophilus asiaticus str. 5a2, Candidatus Amoebophilus asiaticus strain 5a2
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