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mptA mptA moaA moaA Mboo_1709 Mboo_1709 ndk ndk Mboo_1326 Mboo_1326 Mboo_1838 Mboo_1838 mptE mptE mptD mptD Mboo_0848 Mboo_0848 Mboo_0266 Mboo_0266 ilvC ilvC
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query proteins and first shell of interactors
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second shell of interactors
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mptAProtein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (326 aa)    
Predicted Functional Partners:
moaA
Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
    
  0.901
Mboo_1709
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: mhu:Mhun_2811 ribonucleoside-triphosphate reductase, anaerobic.
  
  
  0.837
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.804
Mboo_1326
TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: mhu:Mhun_1167 adenylyl cyclase CyaB, putative.
    
  0.803
Mboo_1838
KEGG: mhu:Mhun_0621 carbonic anhydrase (gamma family Zn(II)-dependent enzymes).
  
  
 0.664
mptE
Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
   
 0.651
mptD
Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
 
   
 0.648
Mboo_0848
TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: mhu:Mhun_0540 dihydroorotase, multifunctional complex type.
  
  
 0.622
Mboo_0266
KEGG: mhu:Mhun_2831 6-pyruvoyl tetrahydropterin synthase and hypothetical protein.
 
   
 0.584
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.551
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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