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lipB lipB lipA lipA gcvH gcvH fabB fabB fabF fabF ETA_30080 ETA_30080 fabV fabV ybeD ybeD bacA bacA ETA_13580 ETA_13580 aceF aceF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
lipBLipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (223 aa)    
Predicted Functional Partners:
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.911
fabB
3-oxoacyl-[acyl-carrier-protein] synthase 1; silverDB:etchr01151; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
 0.813
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
    
 0.813
ETA_30080
3-oxoacyl-[acyl-carrier-protein] synthase II; silverDB:etchr02995; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
 0.813
fabV
Putative short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.
     
  0.800
ybeD
Conserved hypothetical protein YpeD; silverDB:etchr02345; Belongs to the UPF0250 family.
  
  
 0.774
bacA
Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904.
   
 0.657
ETA_13580
8-amino-7-oxononanoate synthase; silverDB:etchr01348.
   
 0.607
aceF
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
 0.603
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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