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upp upp pyrF pyrF Bcav_3297 Bcav_3297 Bcav_2940 Bcav_2940 pyrH pyrH pyrR pyrR Bcav_2186 Bcav_2186 guaA guaA Bcav_2933 Bcav_2933 Bcav_1451 Bcav_1451 Bcav_1683 Bcav_1683
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)    
Predicted Functional Partners:
pyrF
PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.980
Bcav_3297
ATP-binding protein.
  
 0.969
Bcav_2940
PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase.
  
 
 0.962
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.956
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.954
Bcav_2186
Uridine kinase.
  
 0.950
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.944
Bcav_2933
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.936
Bcav_1451
N-isopropylammelide isopropylaminohydrolase; PFAM: Amidohydrolase family.
  
 
 0.925
Bcav_1683
PFAM: Amidohydrolase family.
  
 
 0.925
Your Current Organism:
Beutenbergia cavernae
NCBI taxonomy Id: 471853
Other names: B. cavernae DSM 12333, Beutenbergia cavernae DSM 12333, Beutenbergia cavernae str. DSM 12333, Beutenbergia cavernae strain DSM 12333
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