node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Minf_0751 | hlpA | Minf_0751 | Minf_0749 | Outer membrane protein. | Outer membrane protein. | 0.909 |
Minf_0751 | lpxA | Minf_0751 | Minf_0223 | Outer membrane protein. | Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.574 |
Minf_0751 | lpxA-2 | Minf_0751 | Minf_2130 | Outer membrane protein. | Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.572 |
Minf_0751 | lpxB | Minf_0751 | Minf_1859 | Outer membrane protein. | Lipid A disaccharide synthetase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.445 |
Minf_0751 | lpxC | Minf_0751 | Minf_2131 | Outer membrane protein. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.761 |
Minf_0751 | lpxD | Minf_0751 | Minf_0748 | Outer membrane protein. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.803 |
Minf_0751 | lpxK | Minf_0751 | Minf_1888 | Outer membrane protein. | Tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.525 |
acpP | lpxC | Minf_0431 | Minf_2131 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.935 |
acpP | lpxD | Minf_0431 | Minf_0748 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.780 |
hlpA | Minf_0751 | Minf_0749 | Minf_0751 | Outer membrane protein. | Outer membrane protein. | 0.909 |
hlpA | lpxC | Minf_0749 | Minf_2131 | Outer membrane protein. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.492 |
hlpA | lpxD | Minf_0749 | Minf_0748 | Outer membrane protein. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.875 |
kdsB | kdtA | Minf_0956 | Minf_1736 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.982 |
kdsB | lpxA | Minf_0956 | Minf_0223 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.716 |
kdsB | lpxA-2 | Minf_0956 | Minf_2130 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.703 |
kdsB | lpxB | Minf_0956 | Minf_1859 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | Lipid A disaccharide synthetase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.786 |
kdsB | lpxC | Minf_0956 | Minf_2131 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. | 0.545 |
kdsB | lpxD | Minf_0956 | Minf_0748 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.776 |
kdsB | lpxK | Minf_0956 | Minf_1888 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | Tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.827 |
kdtA | kdsB | Minf_1736 | Minf_0956 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | 0.982 |