node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Minf_0717 | gcvH | Minf_0717 | Minf_2168 | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.883 |
Minf_0717 | gcvP | Minf_0717 | Minf_2170 | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain; Belongs to the GcvP family. | 0.807 |
Minf_0717 | gcvT | Minf_0717 | Minf_2167 | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | Glycine cleavage system T protein (aminomethyltransferase). | 0.870 |
Minf_0717 | lpd | Minf_0717 | Minf_0069 | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | 0.811 |
Minf_0717 | lpd-2 | Minf_0717 | Minf_1002 | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme. | 0.811 |
Minf_0717 | lpd-3 | Minf_0717 | Minf_1201 | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme. | 0.811 |
Minf_0717 | lpd-4 | Minf_0717 | Minf_1635 | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme. | 0.811 |
Minf_1332 | gcvH | Minf_1332 | Minf_2168 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.909 |
Minf_1332 | gcvP | Minf_1332 | Minf_2170 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain; Belongs to the GcvP family. | 0.930 |
Minf_1332 | gcvT | Minf_1332 | Minf_2167 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Glycine cleavage system T protein (aminomethyltransferase). | 0.924 |
Minf_1332 | glyA | Minf_1332 | Minf_1669 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.922 |
Minf_1332 | lpd | Minf_1332 | Minf_0069 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | 0.900 |
Minf_1332 | lpd-2 | Minf_1332 | Minf_1002 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme. | 0.900 |
Minf_1332 | lpd-3 | Minf_1332 | Minf_1201 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme. | 0.900 |
Minf_1332 | lpd-4 | Minf_1332 | Minf_1635 | Serine-pyruvate aminotransferase/aspartate aminotransferase. | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme. | 0.900 |
gcvH | Minf_0717 | Minf_2168 | Minf_0717 | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Proline dehydrogenase and delta 1-pyrroline-5-carboxylate dehydrogenase. | 0.883 |
gcvH | Minf_1332 | Minf_2168 | Minf_1332 | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine-pyruvate aminotransferase/aspartate aminotransferase. | 0.909 |
gcvH | gcvP | Minf_2168 | Minf_2170 | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | Minf_2168 | Minf_2167 | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein (aminomethyltransferase). | 0.999 |
gcvH | glyA | Minf_2168 | Minf_1669 | Glycine cleavage system H protein (lipoate-binding); The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.974 |