STRINGSTRING
mutS2 mutS2 mutS mutS rpsD rpsD ACR72844.1 ACR72844.1 ACR72130.1 ACR72130.1 ACR72843.1 ACR72843.1 polA polA mutL mutL rplD rplD rpsU rpsU dacA dacA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
mutS2DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (787 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
0.932
rpsD
Small subunit ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
   0.775
ACR72844.1
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Psort-B: CytoplasmicMembrane, score:9.49; COG0642 Signal transduction histidine kinase; HMMPfam:IPR003594; HMMPfam:IPR003660; HMMPfam:IPR003661; Gene3D:IPR003594; HMMSmart:IPR003594; HMMSmart:IPR003660; HMMSmart:IPR003661; superfamily:IPR003594; superfamily:IPR009082; K07636 two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR.
       0.759
ACR72130.1
Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; HMMPfam:IPR008532; HMMPfam:IPR008616; superfamily:IPR010979.
 
     0.731
ACR72843.1
Two-component system, OmpR family, response regulator ResD; Psort-B: Cytoplasmic, score:9.98; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; HMMPfam:IPR001789; HMMPfam:IPR001867; BlastProDom:IPR001789; BlastProDom:IPR001867; HMMSmart:IPR001789; superfamily:IPR011006; K07775 two-component system, OmpR family, response regulator ResD.
       0.705
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.701
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.657
rplD
Large subunit ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
   0.624
rpsU
Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0828 Ribosomal protein S21; HMMPfam:IPR001911; BlastProDom:IPR001911; FPrintScan:IPR001911; HMMTigr:IPR001911; ScanRegExp:IPR001911; Belongs to the bacterial ribosomal protein bS21 family.
   
   0.593
dacA
Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
 
     0.588
Your Current Organism:
Eubacterium eligens
NCBI taxonomy Id: 515620
Other names: Eubacterium eligens ATCC 27750, [. eligens ATCC 27750, [Eubacterium] eligens ATCC 27750
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