node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACR72828.1 | guaA | EUBELI_01839 | EUBELI_01806 | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.788 |
ACR72828.1 | mfd | EUBELI_01839 | EUBELI_01914 | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.558 |
ACR72828.1 | pheT | EUBELI_01839 | EUBELI_01342 | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | phenylalanyl-tRNA synthetase; Psort-B: Cytoplasmic, score:9.98; COG0073 EMAP domain; HMMPfam:IPR002547; HMMPfam:IPR005121; HMMPfam:IPR005146; HMMPfam:IPR005147; Gene3D:IPR005121; Gene3D:IPR005147; Gene3D:IPR012340; HMMTigr:IPR004532; superfamily:IPR005121; superfamily:IPR009061; K01888 phenylalanyl-tRNA synthetase; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.732 |
ACR72828.1 | polA | EUBELI_01839 | EUBELI_01072 | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.664 |
ACR72828.1 | pth | EUBELI_01839 | EUBELI_01915 | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.640 |
guaA | ACR72828.1 | EUBELI_01806 | EUBELI_01839 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | 0.788 |
guaA | pheT | EUBELI_01806 | EUBELI_01342 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase; Psort-B: Cytoplasmic, score:9.98; COG0073 EMAP domain; HMMPfam:IPR002547; HMMPfam:IPR005121; HMMPfam:IPR005146; HMMPfam:IPR005147; Gene3D:IPR005121; Gene3D:IPR005147; Gene3D:IPR012340; HMMTigr:IPR004532; superfamily:IPR005121; superfamily:IPR009061; K01888 phenylalanyl-tRNA synthetase; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.955 |
guaA | polA | EUBELI_01806 | EUBELI_01072 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.878 |
guaA | prfB | EUBELI_01806 | EUBELI_00365 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.477 |
guaA | pth | EUBELI_01806 | EUBELI_01915 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.732 |
guaA | rpmA | EUBELI_01806 | EUBELI_01015 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Psort-B: Unknown cell location; COG0211 Ribosomal protein L27; HMMPfam:IPR001684; BlastProDom:IPR001684; FPrintScan:IPR001684; HMMPanther:IPR001684; HMMTigr:IPR001684; ScanRegExp:IPR001684; K02899 large subunit ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.633 |
guaA | tilS | EUBELI_01806 | EUBELI_01870 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.435 |
guaA | ychF | EUBELI_01806 | EUBELI_00724 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.843 |
mfd | ACR72828.1 | EUBELI_01914 | EUBELI_01839 | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | 0.558 |
mfd | polA | EUBELI_01914 | EUBELI_01072 | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.769 |
mfd | prfB | EUBELI_01914 | EUBELI_00365 | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.807 |
mfd | pth | EUBELI_01914 | EUBELI_01915 | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.927 |
mfd | spoVG | EUBELI_01914 | EUBELI_01916 | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Stage V sporulation protein G; Could be involved in septation. | 0.591 |
mfd | tilS | EUBELI_01914 | EUBELI_01870 | Transcription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Cell cycle protein MesJ; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.668 |
pheT | ACR72828.1 | EUBELI_01342 | EUBELI_01839 | phenylalanyl-tRNA synthetase; Psort-B: Cytoplasmic, score:9.98; COG0073 EMAP domain; HMMPfam:IPR002547; HMMPfam:IPR005121; HMMPfam:IPR005146; HMMPfam:IPR005147; Gene3D:IPR005121; Gene3D:IPR005147; Gene3D:IPR012340; HMMTigr:IPR004532; superfamily:IPR005121; superfamily:IPR009061; K01888 phenylalanyl-tRNA synthetase; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; HMMPfam:IPR001763; HMMPfam:IPR011063; Gene3D:IPR014729; HMMSmart:IPR001763; Belongs to the TtcA family. | 0.732 |