node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ctha_0887 | Ctha_2343 | Ctha_0887 | Ctha_2343 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | 0.917 |
Ctha_0887 | clpP | Ctha_0887 | Ctha_0701 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.655 |
Ctha_0887 | dnaK | Ctha_0887 | Ctha_1268 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.908 |
Ctha_0887 | groL | Ctha_0887 | Ctha_1618 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.873 |
Ctha_0887 | groS | Ctha_0887 | Ctha_1617 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.757 |
Ctha_0887 | grpE | Ctha_0887 | Ctha_1823 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.987 |
Ctha_0887 | hslU | Ctha_0887 | Ctha_0182 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.543 |
Ctha_0887 | hslV | Ctha_0887 | Ctha_0181 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | 20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.448 |
Ctha_0887 | htpG | Ctha_0887 | Ctha_2587 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.986 |
Ctha_2343 | Ctha_0887 | Ctha_2343 | Ctha_0887 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | 0.917 |
Ctha_2343 | clpP | Ctha_2343 | Ctha_0701 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.655 |
Ctha_2343 | dnaK | Ctha_2343 | Ctha_1268 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.915 |
Ctha_2343 | groL | Ctha_2343 | Ctha_1618 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.845 |
Ctha_2343 | groS | Ctha_2343 | Ctha_1617 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.757 |
Ctha_2343 | grpE | Ctha_2343 | Ctha_1823 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.965 |
Ctha_2343 | hslU | Ctha_2343 | Ctha_0182 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.543 |
Ctha_2343 | hslV | Ctha_2343 | Ctha_0181 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | 20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.448 |
Ctha_2343 | htpG | Ctha_2343 | Ctha_2587 | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.988 |
clpP | Ctha_0887 | Ctha_0701 | Ctha_0887 | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aba:Acid345_0480 heat shock protein 70. | 0.655 |
clpP | Ctha_2343 | Ctha_0701 | Ctha_2343 | Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Molecular chaperone-like protein; KEGG: aau:AAur_3285 putative DnaK family protein. | 0.655 |