STRINGSTRING
ftsH ftsH Apar_0055 Apar_0055 rplC rplC rplN rplN rplM rplM rplO rplO clpX clpX rpmA rpmA Apar_0107 Apar_0107 rplS rplS Apar_1132 Apar_1132
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. (644 aa)    
Predicted Functional Partners:
Apar_0055
PFAM: band 7 protein; SMART: band 7 protein; KEGG: nar:Saro_3197 band 7 protein.
  
 0.943
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.730
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.723
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.722
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.718
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.717
rpmA
TIGRFAM: ribosomal protein L27; PFAM: ribosomal protein L27; KEGG: aba:Acid345_0019 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.717
Apar_0107
KEGG: bsu:BSU00680 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.714
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 
 0.713
Apar_1132
TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; KEGG: dal:Dalk_1888 ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
   
 
 0.703
Your Current Organism:
Atopobium parvulum
NCBI taxonomy Id: 521095
Other names: A. parvulum DSM 20469, Atopobium parvulum ATCC 33793, Atopobium parvulum DSM 20469, Atopobium parvulum JCM 10300, Atopobium parvulum str. DSM 20469, Atopobium parvulum strain DSM 20469
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