STRINGSTRING
zapB zapB ftsN ftsN PC1_0290 PC1_0290 PC1_4201 PC1_4201 PC1_4228 PC1_4228 PC1_1784 PC1_1784 PC1_0612 PC1_0612 lpoB lpoB PC1_1291 PC1_1291 PC1_0451 PC1_0451 PC1_2544 PC1_2544
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
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[Homology]
Score
zapBProtein of unknown function DUF904; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (79 aa)    
Predicted Functional Partners:
ftsN
Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
   
 0.780
PC1_0290
PFAM: protein of unknown function DUF1043; KEGG: eca:ECA0304 cytochrome d ubiquinol oxidase subunit III.
  
   
 0.775
PC1_4201
PFAM: UspA domain protein; KEGG: eca:ECA0050 universal stress protein A.
  
  
 0.775
PC1_4228
PFAM: DSBA oxidoreductase; KEGG: eca:ECA0020 periplasmic protein disulfide isomerase I.
  
  
 0.773
PC1_1784
PFAM: porin Gram-negative type; KEGG: eca:ECA2542 outer membrane protein; Belongs to the Gram-negative porin family.
  
     0.772
PC1_0612
DNA polymerase III psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.769
lpoB
Membrane lipoprotein lipid attachment site; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
  
     0.754
PC1_1291
PFAM: AsmA family protein; KEGG: eca:ECA1413 putative assembly protein.
  
     0.743
PC1_0451
KEGG: eca:ECA0466 hypothetical protein.
  
     0.733
PC1_2544
PFAM: UvrD/REP helicase; KEGG: eca:ECA1756 DNA helicase IV.
  
     0.733
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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