STRINGSTRING
PC1_1798 PC1_1798 PC1_1799 PC1_1799 hisI hisI hisB hisB PC1_1878 PC1_1878 PC1_2783 PC1_2783 ybeY ybeY PC1_1800 PC1_1800 PC1_1219 PC1_1219 hisD hisD hisF hisF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PC1_1798PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: eca:ECA2529 putative hydrolase; Belongs to the PHP family. (245 aa)    
Predicted Functional Partners:
PC1_1799
PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein.
  
 
 0.831
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-AMP cyclohydrolase; KEGG: eca:ECA2589 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.710
hisB
Histidinol-phosphatase; KEGG: eca:ECA2585 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: imidazoleglycerol-phosphate dehydratase; Polynucleotide kinase 3 phosphatase central region; In the N-terminal section; belongs to the histidinol- phosphatase family.
  
  
 0.546
PC1_1878
Signal transduction histidine kinase, LytS; KEGG: eca:ECA2432 two-component sensor kinase; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
     0.487
PC1_2783
TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: eca:ECA3043 phosphodiesterase.
 
     0.456
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
    0.453
PC1_1800
PFAM: protein of unknown function DUF1439; KEGG: eca:ECA2527 hypothetical protein.
  
   
 0.427
PC1_1219
KEGG: eca:ECA1344 hypothetical protein.
  
     0.415
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
  
 0.414
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.410
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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