node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_1069 | PC1_1377 | PC1_1069 | PC1_1377 | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | 0.800 |
PC1_1069 | PC1_1521 | PC1_1069 | PC1_1521 | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | PFAM: secretion protein HlyD family protein; KEGG: esa:ESA_02550 hypothetical protein. | 0.482 |
PC1_1069 | PC1_2680 | PC1_1069 | PC1_2680 | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: eca:ECA2932 putative outer membrane efflux lipoprotein. | 0.739 |
PC1_1069 | mdtA | PC1_1069 | PC1_2966 | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: eca:ECA3184 multidrug efflux system subunit MdtA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.816 |
PC1_1376 | PC1_1377 | PC1_1376 | PC1_1377 | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | 0.937 |
PC1_1376 | PC1_1521 | PC1_1376 | PC1_1521 | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | PFAM: secretion protein HlyD family protein; KEGG: esa:ESA_02550 hypothetical protein. | 0.731 |
PC1_1376 | PC1_2680 | PC1_1376 | PC1_2680 | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: eca:ECA2932 putative outer membrane efflux lipoprotein. | 0.658 |
PC1_1376 | macB | PC1_1376 | PC1_0769 | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | ABC transporter related; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.918 |
PC1_1376 | mdtA | PC1_1376 | PC1_2966 | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: eca:ECA3184 multidrug efflux system subunit MdtA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.778 |
PC1_1377 | PC1_1069 | PC1_1377 | PC1_1069 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | 0.800 |
PC1_1377 | PC1_1376 | PC1_1377 | PC1_1376 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | 0.937 |
PC1_1377 | PC1_1521 | PC1_1377 | PC1_1521 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | PFAM: secretion protein HlyD family protein; KEGG: esa:ESA_02550 hypothetical protein. | 0.690 |
PC1_1377 | PC1_3923 | PC1_1377 | PC1_3923 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA4131 aminoglycoside/multidrug efflux system. | 0.788 |
PC1_1377 | macB | PC1_1377 | PC1_0769 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | ABC transporter related; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.729 |
PC1_1377 | mdtA | PC1_1377 | PC1_2966 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: eca:ECA3184 multidrug efflux system subunit MdtA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.734 |
PC1_1377 | mdtB | PC1_1377 | PC1_2967 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | PFAM: acriflavin resistance protein; KEGG: eca:ECA3185 multidrug efflux system subunit MdtB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. | 0.520 |
PC1_1377 | mdtC | PC1_1377 | PC1_2968 | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | PFAM: acriflavin resistance protein; KEGG: eca:ECA3186 multidrug efflux system subunit MdtC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. | 0.467 |
PC1_1521 | PC1_1069 | PC1_1521 | PC1_1069 | PFAM: secretion protein HlyD family protein; KEGG: esa:ESA_02550 hypothetical protein. | TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1169 acriflavin resistance protein B. | 0.482 |
PC1_1521 | PC1_1376 | PC1_1521 | PC1_1376 | PFAM: secretion protein HlyD family protein; KEGG: esa:ESA_02550 hypothetical protein. | PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: mms:mma_1065 macrolide ABC efllux protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. | 0.731 |
PC1_1521 | PC1_1377 | PC1_1521 | PC1_1377 | PFAM: secretion protein HlyD family protein; KEGG: esa:ESA_02550 hypothetical protein. | TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pap:PSPA7_2869 outer membrane protein. | 0.690 |