node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TGAM_0001 | asnB | TGAM_0001 | TGAM_1938 | Putative asparagine synthase, glutamine-hydrolyzing. | Asparagine synthase (glutamine-hydrolyzing) (asnB). | 0.959 |
TGAM_0001 | purB | TGAM_0001 | TGAM_1551 | Putative asparagine synthase, glutamine-hydrolyzing. | Adenylosuccinate lyase (purB); Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.920 |
TGAM_0001 | purD | TGAM_0001 | TGAM_0750 | Putative asparagine synthase, glutamine-hydrolyzing. | Phosphoribosylamine--glycine ligase (purD). | 0.798 |
TGAM_0001 | purE | TGAM_0001 | TGAM_0747 | Putative asparagine synthase, glutamine-hydrolyzing. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit (AIR carboxylase) (purE); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.722 |
TGAM_0001 | purL | TGAM_0001 | TGAM_0756 | Putative asparagine synthase, glutamine-hydrolyzing. | Phosphoribosylformylglycinamidine synthase II, purL component (purL); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.934 |
TGAM_0001 | purM | TGAM_0001 | TGAM_0637 | Putative asparagine synthase, glutamine-hydrolyzing. | Phosphoribosylformylglycinamidine cyclo-ligase (purM). | 0.848 |
TGAM_0001 | purQ | TGAM_0001 | TGAM_0755 | Putative asparagine synthase, glutamine-hydrolyzing. | Phosphoribosylformylglycinamidine synthase I, purQ component (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and [...] | 0.878 |
TGAM_0001 | purS | TGAM_0001 | TGAM_0754 | Putative asparagine synthase, glutamine-hydrolyzing. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component (purS); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and Pur [...] | 0.848 |
TGAM_0001 | purT | TGAM_0001 | TGAM_0638 | Putative asparagine synthase, glutamine-hydrolyzing. | Phosphoribosylglycinamide formyltransferase 2 (purT); Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.785 |
asnB | TGAM_0001 | TGAM_1938 | TGAM_0001 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Putative asparagine synthase, glutamine-hydrolyzing. | 0.959 |
asnB | purB | TGAM_1938 | TGAM_1551 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Adenylosuccinate lyase (purB); Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.920 |
asnB | purD | TGAM_1938 | TGAM_0750 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Phosphoribosylamine--glycine ligase (purD). | 0.823 |
asnB | purE | TGAM_1938 | TGAM_0747 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Phosphoribosylaminoimidazole carboxylase, catalytic subunit (AIR carboxylase) (purE); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.762 |
asnB | purL | TGAM_1938 | TGAM_0756 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Phosphoribosylformylglycinamidine synthase II, purL component (purL); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.934 |
asnB | purM | TGAM_1938 | TGAM_0637 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Phosphoribosylformylglycinamidine cyclo-ligase (purM). | 0.870 |
asnB | purQ | TGAM_1938 | TGAM_0755 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Phosphoribosylformylglycinamidine synthase I, purQ component (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and [...] | 0.878 |
asnB | purS | TGAM_1938 | TGAM_0754 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component (purS); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and Pur [...] | 0.848 |
asnB | purT | TGAM_1938 | TGAM_0638 | Asparagine synthase (glutamine-hydrolyzing) (asnB). | Phosphoribosylglycinamide formyltransferase 2 (purT); Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.810 |
purB | TGAM_0001 | TGAM_1551 | TGAM_0001 | Adenylosuccinate lyase (purB); Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Putative asparagine synthase, glutamine-hydrolyzing. | 0.920 |
purB | asnB | TGAM_1551 | TGAM_1938 | Adenylosuccinate lyase (purB); Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Asparagine synthase (glutamine-hydrolyzing) (asnB). | 0.920 |