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rlmM rlmM Tola_0925 Tola_0925 Tola_2881 Tola_2881 Tola_0488 Tola_0488 nfuA nfuA Tola_0711 Tola_0711 yihI yihI Tola_1566 Tola_1566 Tola_1349 Tola_1349 Tola_0597 Tola_0597 syd syd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
rlmMPutative RNA 2'-O-ribose methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (366 aa)    
Predicted Functional Partners:
Tola_0925
PFAM: 37 kDa nucleoid-associated protein; KEGG: aha:AHA_1666 nucleoid-associated protein NdpA.
  
    0.670
Tola_2881
PFAM: protein of unknown function DUF423; KEGG: vch:VC0897 hypothetical protein.
  
  
 0.564
Tola_0488
Transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aha:AHA_1147 DNA-binding transcriptional activator GcvA.
  
    0.553
nfuA
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.551
Tola_0711
PFAM: protein of unknown function DUF6 transmembrane; KEGG: aha:AHA_0045 hypothetical protein.
 
     0.515
yihI
Protein of unknown function DUF414; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
     0.490
Tola_1566
PFAM: Sporulation domain protein; KEGG: asa:ASA_2528 DedD protein.
  
     0.476
Tola_1349
PFAM: protein of unknown function DUF330; KEGG: pmy:Pmen_0370 hypothetical protein.
  
     0.466
Tola_0597
D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: aha:AHA_2649 FAD linked oxidase.
  
     0.448
syd
Syd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.430
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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